17th IHIWS/Immunogenetics Symposium: Sept 6–10, 2017
Conference: Sep 10, 2017
The 17th IHIWS will be held at Asilomar Conference Grounds, located in Pacific Grove, California. Lodging reservations should be made by going to the conference accommodations webpage at https://aws.passkey.com/event/49031649/owner/10793795/home. We recommend staying at or very near the event site in order to take advantage of all of the available activities and meals.
The registration fee covers all workshop sessions and coffee breaks on Wednesday-Sunday, opening reception on 9/6 and a strolling dinner reception on 9/9. Register to attend the event here: http://17ihiw.org/event-registration
The program includes a total of Six Symposia, International Immunogenetics Conference and International Histocompatibility and Immunogenetics Workshop (IHIWS) Activities.
Schedule and Program
Wednesday, September 6, 2017
15:00 – 19:00 | Registration & check in |
15:00 – 16:00 | PM Coffee, Merrill Hall |
18:00 – 19:00 | Dinner, Crocker Dining Hall |
19:00 – 20:00 | Opening Ceremony, Merrill Hall |
Evolution of IHIWS, past and present
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20:00 – 21:30 | Welcome reception: Light hors d’oeuvres, dessert & wine/beer, Merrill Hall |
Thursday, September 7, 2017
07:30 – 08:30 | Breakfast: Crocker Dining Hall |
08:30 – 09:45 | Symposium: Population Genetics, Merrill Hall Moderator: Marcelo Fernandez-Viña, Jill Hollenbach
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09:45 – 10:15 | Morning Coffee break, Merrill Hall |
10:15 – 12:00 | Breakout Session #1a
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12:00 – 13:00 | Lunch & Group Photo, Crocker Dining Hall |
13:00 – 14:00 | Symposium: Nomenclature and Disease Association, Merrill Hall Moderators: Erik Thorsby, Wolfgang R Mayr
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14:00 – 15:45 | Workshop-Activities, Merrill Hall Component: Bioinformatics Moderators: Martin Maiers, Steven Mack |
14:00 – 15:00 | 17th IHIWS Database |
14:00 – 14:20 | Uniform HLA Data Collection and Storage Steven Mack/Chia-Jung Chang |
14:20 – 14:35 | Family Haplotype Analysis Kazutoyo Osoegawa |
14:35 – 15:00 | Methods for Population Analysis
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15:00 – 15:15 | Gene Feature Enumeration and Allele Calling Tool Mike Halagan |
15:15 – 15:30 | Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles James Robinson |
15:30 – 15:45 | STR sequencing through HLA genes Erik Rozemuller |
15:45 – 16:15 | Afternoon Coffee break, Merrill Hall |
16:15 – 17:00 | Breakout Session #1b
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17:00 – 18:00 | Breakout Session continued for Epitopes component |
17:00 – 18:00 | Workshop-Activities, Merrill Hall Component: NGS HLA Related Projects Moderators: Elissaveta Naumova, Marcel Tilanus |
17:00 – 17:20 | Extension of HLA allele sequences by full-length HLA allele-specific hemizygous Sanger sequencing (SSBT) Christien E Voorter |
17:20 – 17:40 | Immunogenetics of Aging Milena Ivanova |
17:40 – 18:00 | Disease Association Jorge Oksenberg |
18:00 – 19:00 | Dinner, Crocker Dining Hall |
19:00 – 20:00 | Symposium: Imputation & TCR, Merrill Hall Moderators: Dominique Charron, Elissaveta Naumova
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20:00 – 21:30 | Breakout Session #1c
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Friday, September 8, 2017
07:30 – 08:50 | Breakfast, Crocker Dining Hall |
07:30 – 10:00 | Breakfast (by invitation only), Woodlands Room WHO Nomenclature Committee for Factors of the HLA System Steven GE Marsh |
09:00 – 10:00 | Symposium: NGS HLA, Merrill Hall Moderators: J Alejandro Madrigal, Henry A Erlich
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10:00 – 10:30 | Morning Coffee break, Merrill Hall |
10:30 – 12:00 | Workshop-Activities, Merrill Hall Component: NGS HLA Projects Moderator: Gottfried Fisher, Marcelo Fernandez-Vina |
10:30 – 11:10 | Workshop cell lines NGS HLA typing |
10:30 – 10:45 | Workshop Quality Control Diane De Santis, Sabine Wenda |
10:45 – 11:00 | Cell Lines NGS Workshop Report Lisa Creary |
11:00 – 11:10 | Single Molecule Real-Time (SMRT®) DNA sequencing of HLA genes at unambiguous, high-resolution from 126 International HLA and Immunogenetics Workshop cell lines Thomas Turner |
11:10 – 12:00 | IHIWS Registries report |
11:10 – 11:20 | Jurgen Sauter (DKMS) |
11:20 – 11:30 | Pablo Galarza (INCUCAI) |
11:30 – 11:45 | Yung-Tsi Bolon, Bob Milius (NMDP) |
11:45 – 12:00 | Whole-gene HLA class I nucleotide sequence variation and evolution among alleles from >100,000 individuals (Nezih Cereb) |
12:00 – 13:00 | Lunch, Crocker Dining Hall |
13:00 – 15:15 | Breakout Session #2a
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13:00 – 15:15 | Workshop-Activities, Merrill Hall Component: NGS HLA Projects, Population Genetics Moderators: José Manuel Nunes, Steven Mack |
13:00 – 13:20 | CWD Summaries Carolyn Hurley, Jason Dehn |
13:20 – 13:35 | Dual redundant reference sequencing: characterizing diversity Irina Böhme |
13:35 – 13:50 | Rare & Novel HLA Alleles by NGS HLA — Coding non-coding polymorphism Medhat Askar |
13:50 – 14:30 | IHIWS Families project contributors, individual brief reports |
14:30 – 15:15 | IHIWS Unrelated project contributors, individual brief reports |
15:15 – 15:45 | Afternoon Coffee break, Merrill Hall |
15:45 – 16:45 | Workshop-Activities, Merrill Hall Component: NGS HLA Family and unrelated studies Summaries Moderators: Dominique Charron, Carolyn Hurley |
1545 – 1615 | Haplotypes in Families Report Kazutoyo Osoegawa, Medhat Askar |
1615 – 1645 | Unrelated Population Analysis Report Marcelo Fernandez-Vina |
16:45 – 18:15 | Breakout Session #2b
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16:45 – 17:45 | Symposium: NGS KIR, Merrill Hall Moderators: Daniel E Geraghty, Mary Carrington
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17:45 – 18:15 | Workshop-Activities, Merrill Hall Component: NGS of Full-length KIR Genes Moderator: Paul Norman
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18:15 – 18:45 | Sponsor Presentations:
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18:45 – 19:45 | Dinner, Crocker Dining Hall |
19:45 – 21:30 | Wine Tasting: A Taste of Monterey, Sea Scape Room Sponsored by One Lambda, a Thermo Fisher Scientific Brand |
Saturday, September 9, 2017
07:30 – 08:50 | Breakfast, Crocker Dining Hall |
07:30 – 08:50 | IHIWS Councilors Breakfast Meeting, Woodlands Room (By Invitation Only) Chairs: Derek Middleton and Steven GE Marsh, IHIWS PresidentsAgenda:
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09:00 – 12:00 | Symposium: Hematopoietic Cell Transplantation (HCT), Merrill Hall Moderators: Effie W Petersdorf, Carlheinz Muller |
09:05 – 10:00 | Symposium #S5a |
09:05 – 09:15 | IHWG Study of the Role of Ethnicity in HLA-mismatched HCT Yasuo Morishima, Aichi Medical University |
09:15 – 09:25 | French study about effect of DRB and DPB1 mismatches on outcome after HSCT Valerie Dubois, EFS Auvergne Rhone Alpes |
09:25 – 09:35 | JMDP HLA-DP study update Satoko Morishima, University of the Ryukyus |
09:35 – 09:45 | Biological mechanisms controlling alloreactivity to HLA-DP Esteban Arrieta Bolaños, Institute for Experimental Cellular Therapy |
09:45 – 10:00 | Panel discussion |
10:00 – 10:30 | Morning Coffee break, Merrill Hall |
10:30 – 12:00 | Symposium #S5b |
10:30 – 10:50 | The impact of definitive HLA typing on unrelated donor hematopoietic stem cell transplant outcome – Does TGS typing make a difference? Neema Mayor, Anthony Nolan Research Institute |
10:50 – 11:10 | Role of KIR in Transplantation Katharine Hsu, Memorial Sloan Kettering Cancer Center |
11:10 – 11:20 | Effect of MICA and HLA-E in HSCT: Results of a German Cohort Joannis Mytilineos, Institute of Transfusion Medicine (IKT) |
11:20 – 11:30 | Role of MICA – The US Experience Medhat Askar, Baylor University Medical Center |
11:30 – 11:40 | MICA and GVHD Seiamak Bahram, Université de Strasbourg |
11:40 – 12:00 | Panel discussion |
12:00 – 13:00 | Lunch, Crocker Dining Hall |
13:00 – 14:00 | Symposium: Solid Organ Transplant, Merrill Hall Moderators: Rhonda Holdsworth, Narinder Mehra
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14:00 – 15:30 | Workshop-Activities, Merrill Hall Component: Mapping of Serologic Epitopes Moderators: Dolly Tyan, Frans HJ Claas |
14:00 – 14:05 | What is an epitope? Frans HJ Claas |
14:05 – 14:25 | Brazil Analysis Semiramis Jamil Hadad do Monte |
14:25 – 14:45 | Netherlands Analysis Sebastiaan Heidt, Cynthia Kramer |
14:45 – 15:05 | Stanford Analysis and Automation of Donor Specific Antibody Assignment and Virtual Crossmatching Chia-Jung Chang and Dolly Tyan |
15:05 – 15:15 | PIRCHE for T cell help Eric Spierings |
15:15 – 15:25 | Variations in cell surface expression and stability among HLA-B antigens Malini Raghavan |
15:25 – 15:30 | Epitope Nomenclature – Where do we go next? |
15:30 – 16:00 | Afternoon Coffee break, Merrill Hall |
16:00 – 16:45 | Sponsor Presentations:
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16:45 – 17:15 | Going to the Future: HLA Genomics Moderators: Martin Maiers, John TrowsdaleGenomics of MHC micro RNA Dimitri Monos, The Children’s Hospital of Philadelphia |
16:45 – 17:00 | Genomics of MHC micro RNA Dimitri Monos, The Children’s Hospital of Philadelphia |
17:00 – 17:15 | Full Characterization of Human MHC and KIR haplotypes and genotypes by de Novo whole genome sequencing on PacBio Sequel platform Nezih Cereb, HistoGenetics |
17:15 – 17:35 | Marcelo Fernandez-Vina, Stanford University, Workshop remarks, Merrill Hall |
17:35 – 18:30 | Breakout Session #3a
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19:00 – 22:00 | DINNER CLOSING RECEPTION, Asilomar Meadow/ Bar-B Que Area Music by Wild Blue Quartet Strolling Dinner, Includes wine/beer/soda |
Sunday, September 10, 2017
08:00 – 12:00 | Checkout |
07:30 – 08:30 | Breakfast, Crocker Dining Hall |
08:30 | 17th IHIWS Summaries, Merrill Hall Moderators: Derek Middleton, Gottfried Fischer |
08:30 – 08:50 | Informatics and Population Genetics Steve Mack, Children’s Hospital Oakland Research Institute |
08:50 – 09:20 | HLA typing by NGS Marcelo Fernandez Vina, Stanford University |
09:20 – 09:40 | 17th IHIWS KIR Component QC and Sample Collection results Cynthia Vierra-Green, CIBMTR Jill Hollenbach, UCSF |
09:40 – 10:10 | Epitope Analyses Dolly Tyan, Stanford University Frans HJ Claas, LUMC |
10:10 – 10:30 | Immunogenetics of HSC Transplantation Effie W Petersdorf, Fred Hutchinson Cancer Research Center |
10:30 – 11:00 | Morning Coffee break, Merrill Hall |
11:00 – 12:00 | Immunogenetics Conference Moderators: Steven GE Marsh, Marcel GJ Tilanus |
11:00 – 11:30 | C1-Immunogenetics Conference, Merrill Hall The industrial revolution of the MHC John Trowsdale, University of Cambridge |
11:30 – 12:00 | C2-Immunogenetics Conference, Merrill Hall HLA Diversity Marcelo Fernandez-Viña |
12:00 – 13:00 | Lunch, Crocker Dining Hall |
13:00 – 15:00 | Immunogenetics Conference Moderators: Dominique C Charron, Clara Gorodezky |
13:00 – 13:30 | C3-Immunogenetics Conference, Merrill Hall Antigen Presenting Structures James McCluskey, University of Melbourne |
13:30 – 14:00 | C4-Immunogenetics Conference, Merrill Hall Elevated HLA-A expression impairs HIV control through increased natural killer cell inhibition Mary Carrington, Leidos Biomedical Research Inc. |
14:00 – 14:30 | C5-Immunogenetics Conference, Merrill Hall KIR and HLA interactions Peter Parham, Stanford University |
14:30 – 15:00 | C6-Immunogenetics Conference, Merrill Hall HLA as predominant genetic factors for autoimmune diseases, infectious diseases, and adverse drug reactions Katsushi Tokunaga, University of Tokyo, Graduate School of Medicine |
15:00 – 15:30 | Afternoon Coffee break, Merrill Hall |
15:30 – 16:30 | Immunogenetics Conference Moderators: Steven GE Marsh, Walter F Bodmer |
15:30 – 16:00 | C7-Immunogenetics Conference, Merrill Hall Histocompatibiity testing for organ transplantation: Present and Future Frans HJ Claas, LUMC |
16:00 – 16:30 | C8-Immunogenetics Conference, Merrill Hall Immunogenetics of Allogeneic Hematopoietic Cell Transplantation Effie W Petersdorf, Fred Hutchinson Cancer Research Center |
16:30 – 17:00 | Closing Remarks by Chair: Marcelo Fernandez-Vina, Stanford University |
17:20 | Bus Transport to San Francisco general |
17:20 – 18:20 | Bus Transport to Councilor’s dinner & SF |
18:20 – 20:30 | IHIWS Council Members Dinner, PortaBella Restaurant (By Invitation Only)
Website: http://portabellacarmel.com James McCluskey Moderator, Agenda to be defined by current Presidents |